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少精子症不育患者与正常生育男性血清和精液中锌水平的相互关系。

Inter-relationship of zinc levels in serum and semen in oligospermic infertile patients and fertile males.

作者信息

Mohan H, Verma J, Singh I, Mohan P, Marwah S, Singh P

机构信息

Medical College & Hospital, Rohtak, Haryana.

出版信息

Indian J Pathol Microbiol. 1997 Oct;40(4):451-5.

PMID:9444854
Abstract

Infertility is a problem affecting 10-12% of couples. Zinc is necessary for growth, sexual maturation and reproduction. Semen analysis is helpful in ascertaining the evidence of spermatogenesis, sperm transport, sperm quantity and quality and also provides clue to the functioning of the accessory glands i.e. seminal vesicles and prostate. The present study was conducted in 50 oligospermic infertile males and control group consisting of 25 normospermic known fertile males. Semen and Serum samples were obtained from each case in study as well as control group. Semen and serum were processed by wet ash method. The seminal and serum zinc levels of each case in study and control group were estimated. Statistically, serum zinc and semen zinc levels were significantly lower in infertile patients than fertile males. A significant correlation was observed between serum and semen zinc levels in study group.

摘要

不孕症是一个影响10%至12%夫妇的问题。锌对于生长、性成熟和生殖是必需的。精液分析有助于确定精子发生、精子运输、精子数量和质量的证据,还能为附属腺体即精囊和前列腺的功能提供线索。本研究对50名少精子症不育男性和由25名已知正常精子的可育男性组成的对照组进行。从研究组和对照组的每个病例中获取精液和血清样本。精液和血清采用湿灰化法处理。对研究组和对照组每个病例的精液和血清锌水平进行了测定。统计学上,不育患者的血清锌和精液锌水平显著低于可育男性。研究组中观察到血清锌和精液锌水平之间存在显著相关性。

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