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正常及光剥夺家兔视网膜电图的发展

The development of the electroretinogram in normal and light-deprived rabbits.

作者信息

Reuter J H

出版信息

Pflugers Arch. 1976 May 6;363(1):7-13. doi: 10.1007/BF00587395.

Abstract
  1. The development of the ERG of the pigmented Dutch Belted rabbits is completed before the age of 5 weeks. 2. The a-wave amplitude attains the adult value by the age of 40 days. 3. The b-wave amplitude development is fastest before the age of 40 days but continues to increase afterwards probably due to increase of eye size. 4. Both a- and b-wave peak-latencies decrease with increasing age to the age of 40 days. 5. The b-wave seems to originate from two processes, one leading to a "slow b-wave" showing low threshold, long peak-latency and in adult animals no oscillatory potentials, which dominates the low stimulus intensity response. The other, a "fast b-wave" of higher threshold, shorter latency, and showing oscillatory potentials, dominates the high stimulus intensity response. 6. Light deprivation does not retard the early development of the ERG in rabbits.
摘要
  1. 荷兰花斑兔视网膜电图(ERG)的发育在5周龄前完成。2. a波振幅在40日龄时达到成年值。3. b波振幅在40日龄前发育最快,但之后可能由于眼球大小增加而持续上升。4. a波和b波的峰潜伏期在40日龄前随年龄增长而缩短。5. b波似乎源于两个过程,一个产生“慢b波”,其阈值低、峰潜伏期长,成年动物无振荡电位,在低刺激强度反应中占主导。另一个是“快b波”,阈值较高、潜伏期较短且有振荡电位,在高刺激强度反应中占主导。6. 光剥夺不会延缓兔ERG的早期发育。

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