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[左心房原发性平滑肌肉瘤——罕见病例。病例报告及文献综述]

[Primary leiomyosarcoma in the left atrium--a rarity. Case report and literature review].

作者信息

Guschmann M, Hofmeister J

机构信息

Institut für Pathologie des Virchow-Klinikums, Humboldt Universität zu Berlin.

出版信息

Pathologe. 1997 Nov;18(6):474-9. doi: 10.1007/s002920050245.

Abstract

The case presents a 61 year old woman which came into the hospital with left heart failure. After an unsuccessful trial to treat the heart failure in an habitual method the echocardiographic showed a mass lesion which had filled out mostly of the left atrium. Histological features demonstrated a leiomyosarcoma with an origin from the wall of the left atrium. Immunohistochemical preparations revealed a positivity for actin, desmin and vimentin. Despite an operative resection and an attach of polychemotherapy it developed a local relapse and multiple lymph node metastases. Within the scope of this case report apart from an detailed bibliography it ought to be discussed the origin of the tumor into the atrium and the differential diagnosis from other sarcoma.

摘要

该病例为一名61岁女性,因左心衰竭入院。采用常规方法治疗心力衰竭未成功后,超声心动图显示左心房大部分被一个肿块占据。组织学特征显示为平滑肌肉瘤,起源于左心房壁。免疫组织化学检查显示肌动蛋白、结蛋白和波形蛋白呈阳性。尽管进行了手术切除并联合多药化疗,但仍出现局部复发和多处淋巴结转移。在本病例报告范围内,除了详细的参考文献外,还应讨论肿瘤在心房的起源以及与其他肉瘤的鉴别诊断。

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