Hosaka S, Suzuki S, Kato J, Sasaki H, Fukuda N, Katahira S, Yoshii S, Kamiya K, Tada Y
Department of Surgery, Yamanashi Medical University, Japan.
Nihon Kyobu Geka Gakkai Zasshi. 1997 Dec;45(12):1916-21.
To prevent the atheroembolic complications such as brain infarction due to the manipulation of atherosclerotic ascending aorta during cardiac surgery, the ascending aorta of 55 patients including 6 emergencies (mean age: 67.7 +/- 6.9 years, valvular disease: n = 12, ischemic heart disease only or combined with valvular disease: n = 43) were evaluated with intraoperative echography as a routine, to enable a proper placement of the cannulae, clamp etc. Irregular elevated lesions into the aortic lumen from the intima were identified in 7 patients (13%, mean age: 71.0 +/- 6.9 years) of ischemic heart disease, which included 2 emergent cases. Arch cannulation was employed in 3 patients with wide-spread lesions on the posterior wall and femoral cannulation was done in 1 patient with wide-spread lesions on the anterior wall. Two of these patients received CABG with in situ arterial conduits under ventricular fibrillation, and the other 2 patients received CABG with aortic cross clamping at the lesion-free site during proximal anastomosis of vein grafts (single clamp technique). Two patients with localized lesion were done CABG with partial aortic clamping and one of them had cerebral infarction during the operation. We recognized that manipulation of the ascending aorta has to be done with a meticulous care and well away from the diseased site. In another patient with localized lesion, the arch cannulation and the single clamp technique were used 2 cm away from that lesion. The brain infarcted patient completely recovered without any sequelae and the others also had no atheroembolic complications. Although calcified lesions on CT were correlated with atheromatous lesions on echogram (p = 0.004), these atheromatous plaques were not detected by enhanced CT, except in only one patient. For screening of the atherosclerosis of ascending aorta, the CT examination was not so effective and the intraoperative echography was the most sensitive and could be easily accomplished. In conclusion, in order to prevent the atheroembolism that might occur due to the improper manipulation of the diseased ascending aorta during usual procedures, surgical strategies have to be modified according to the position, extent and quality of the atherosclerotic lesions, diagnosed by intraoperative echoscanning of the aorta.
为预防心脏手术中因操作动脉粥样硬化性升主动脉而导致的动脉粥样硬化栓塞并发症,如脑梗死,对55例患者(包括6例急诊患者,平均年龄:67.7±6.9岁,瓣膜病:n = 12,单纯缺血性心脏病或合并瓣膜病:n = 43)的升主动脉进行术中超声心动图常规评估,以确保插管、夹钳等的正确放置。在7例(13%,平均年龄:71.0±6.9岁)缺血性心脏病患者中,发现有从内膜突入主动脉腔的不规则隆起病变,其中包括2例急诊病例。3例后壁病变广泛的患者采用了弓部插管,1例前壁病变广泛的患者采用了股动脉插管。其中2例患者在心室颤动下采用原位动脉移植物进行冠状动脉旁路移植术(CABG),另外2例患者在静脉移植物近端吻合期间在无病变部位进行主动脉交叉夹闭的情况下接受了CABG(单夹技术)。2例局限性病变患者进行了部分主动脉夹闭的CABG,其中1例在手术期间发生了脑梗死。我们认识到,对升主动脉的操作必须谨慎进行,且要远离病变部位。在另1例局限性病变患者中,在距病变2 cm处采用了弓部插管和单夹技术。脑梗死患者完全康复,无任何后遗症,其他患者也未发生动脉粥样硬化栓塞并发症。尽管CT上的钙化病变与超声心动图上的动脉粥样硬化病变相关(p = 0.004),但除1例患者外,增强CT未检测到这些动脉粥样硬化斑块。对于升主动脉动脉粥样硬化的筛查,CT检查效果不佳,术中超声心动图最为敏感且易于完成。总之,为预防在常规手术过程中因对病变升主动脉操作不当而可能发生的动脉粥样硬化栓塞,必须根据通过主动脉术中超声扫描诊断的动脉粥样硬化病变的位置、范围和性质来调整手术策略。