Okada N, Hamada M, Ogiwara I, Ohshima K
Faculty of Bioscience and Biotechnology, Tokyo Institute of Technology, Yokohama, Japan.
Gene. 1997 Dec 31;205(1-2):229-43. doi: 10.1016/s0378-1119(97)00409-5.
There are now five reported examples in which the 3' ends of tRNA-derived SINEs are derived from the 3' ends of LINEs. These examples include representative sequences from turtles, fish, mammals and plants (Ohshima et al., 1996, Mol. Cell. Biol., 16, 3756 3764; Okada and Hamada, 1997, J. Mol. Evol. 44, Suppl 1:S52-S56). In this review, we discuss the generality of this architecture of SINEs, adding new examples of pairs of SINEs and LINEs, which include one complete and two probable examples from this laboratory and one complete example from the laboratory of Arian Smit. This organization of SINEs and LINEs provides the basis for a simple general scheme by which SINEs might acquire retropositional activity.
目前已有五个报道的例子,其中tRNA衍生的短散在重复元件(SINEs)的3'末端源自长散在重复元件(LINEs)的3'末端。这些例子包括来自龟类、鱼类、哺乳动物和植物的代表性序列(大岛等人,1996年,《分子细胞生物学》,16卷,3756 - 3764页;冈田和滨田,1997年,《分子进化杂志》,44卷,增刊1:S52 - S56)。在本综述中,我们讨论了这种SINEs结构的普遍性,增加了SINEs与LINEs配对的新例子,其中包括来自本实验室的一个完整例子和两个可能的例子,以及来自阿里安·斯密特实验室的一个完整例子。SINEs和LINEs的这种组织方式为一个简单的通用方案提供了基础,通过该方案SINEs可能获得逆转座活性。