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公共资助的艾滋病病毒咨询与检测项目中艾滋病病毒血清阳性率的趋势:对预防政策的影响

Trends in HIV seropositivity in publicly funded HIV counseling and testing programs: implications for prevention policy.

作者信息

Valdiserri R O, Weber J T, Frey R

机构信息

Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA.

出版信息

Am J Prev Med. 1998 Jan;14(1):31-42. doi: 10.1016/s0749-3797(97)00012-3.

Abstract

INTRODUCTION

We describe trends in seropositivity among clients attending publicly funded HIV counseling and testing sites across the United States and discuss implications for prevention policy.

METHODS

The present analysis used client-level data from 1990 through 1994 for 26 of 65 state, territorial, and local health departments receiving Centers for Disease Control and Prevention funds. Logistic regression was used to predict the proportion of HIV tests that were positive. Curves were created representing adjusted HIV seropositivity trends for 1990 through 1994.

RESULTS

HIV seropositivity rates were higher before 1992. Throughout, rates were higher among men, most racial/ethnic minorities tested, and persons 30 years or older. Although rates for men remained higher than those for women, the gap has narrowed in recent years. For both men and women, rates remained low for those reporting heterosexual activity as their only potential risk for HIV. Over time, more high-risk seronegatives are being repeatedly tested.

CONCLUSIONS

Lower, stabilized seropositivity rates after 1992 reflect large increases in testing volume, increasing frequency of repeat testing, and fewer asymptomatic-infected persons entering this public system. Various program innovations including enhanced outreach, improved access, rapid testing, and client-centered counseling should be considered as strategies to increase the number of infected persons who learn their serostatus early and enter into medical care.

摘要

引言

我们描述了美国各地参加公共资助的艾滋病毒咨询和检测点的客户血清阳性率的趋势,并讨论了对预防政策的影响。

方法

本分析使用了1990年至1994年期间65个州、地区和地方卫生部门中26个接受疾病控制和预防中心资金的部门的客户层面数据。使用逻辑回归来预测呈阳性的艾滋病毒检测比例。绘制了代表1990年至1994年调整后的艾滋病毒血清阳性率趋势的曲线。

结果

1992年之前艾滋病毒血清阳性率较高。总体而言,男性、大多数接受检测的种族/族裔少数群体以及30岁及以上人群的血清阳性率较高。虽然男性的血清阳性率仍然高于女性,但近年来差距已经缩小。对于男性和女性来说,那些报告异性性行为是其唯一潜在艾滋病毒风险的人的血清阳性率仍然较低。随着时间的推移,越来越多的高危血清阴性者被反复检测。

结论

1992年之后血清阳性率降低并趋于稳定,这反映了检测量的大幅增加、重复检测频率的提高以及进入这个公共系统的无症状感染者减少。应考虑各种项目创新,包括加强外展、改善可及性、快速检测和以客户为中心的咨询,作为增加早期了解其血清状态并接受医疗护理的感染者数量的策略。

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