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[动脉粥样硬化性黄斑营养不良的新治疗方法]

[New method of atherosclerotic macular dystrophies treatment].

作者信息

Basinskiĭ S N, Krasnogorskaia V N

出版信息

Vestn Oftalmol. 1997 Nov-Dec;113(6):17-9.

PMID:9483992
Abstract

The authors analyze the results of treating atherosclerotic maculodystrophies by direct laser phoresis. The method consists in insertion of a collagen infusion system in Tenon's space. Drugs (nicotinic acid or xanthinol nicotinate) are delivered to the posterior compartment of the eye through this system. Then a light guide is inserted in the tube and a 2-min session of low-intensity He-Ne laser exposure is performed at a wavelength of 630 nm, and 10 mWt/cm2 flow power density (7 to 10 sessions per course). Clinical studies showed that vision acuity increased by an average of 0.08 diopters, or by 40% of the initial level, in 72% of cases. The peripheral visual field extended by an average of 51.4 degrees for 8 meridians in 95% of patients. The index of critical frequency of flashings fusing and the frequency-contrast characteristics improved in 85% of cases. The rheography improved by 34.5% of the initial level. A stable improvement was observed for 12 months after a course of direct laser phoresis in 97.5% of patients. Hence, the new method is simple and recommended for the treatment of atherosclerotic maculodystrophies.

摘要

作者分析了直接激光电泳治疗动脉粥样硬化性黄斑营养不良的结果。该方法是在眼球筋膜囊内插入胶原输注系统。药物(烟酸或烟醇)通过该系统输送到眼后房。然后将光导插入管中,以630nm波长、10mWt/cm²的流量功率密度进行2分钟的低强度氦氖激光照射(每个疗程7至10次)。临床研究表明,72%的病例中视力平均提高了0.08屈光度,即初始水平的40%。95%的患者中,周边视野8条子午线平均扩展了51.4度。85%的病例中闪光融合临界频率指数和频率对比特性得到改善。血流图改善至初始水平的34.5%。97.5%的患者在直接激光电泳疗程后12个月观察到稳定改善。因此,该新方法简单,推荐用于治疗动脉粥样硬化性黄斑营养不良。

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