A novel photoaffinity probe for the LTD4 receptor.
作者信息
Gallant M, Sawyer N, Metters K M, Zamboni R J
机构信息
Merck Frosst Centre for Therapeutic Research, Pointe Claire-Dorval, Québec, Canada.
出版信息
Bioorg Med Chem. 1998 Jan;6(1):63-72. doi: 10.1016/s0968-0896(97)10011-6.
PMID:9502106
Abstract
A novel photoaffinity probe for the leukotriene D4 receptor (LTD4) is described. L-745310, which is structurally related to the potent LTD4 antagonist MK-0476 (Singulair), was found to selectively label a 43-kDa protein in guinea-pig lung membrane previously identified as the LTD4 receptor.
摘要
Zotero 插件