Wen Z C, Chen S A, Tai C T, Huang J L, Chang M S
Department of Medicine, Provincial Hsin-Chu Hospital, Taipei, Taiwan, Republic of China.
J Am Coll Cardiol. 1998 Mar 1;31(3):602-7. doi: 10.1016/s0735-1097(97)00555-x.
This study sought to study the change in autonomic tone that precedes the initiation of paroxysmal atrial flutter.
An abrupt change in the autonomic tone of the heart is an important initiating factor in the pathogenesis of ventricular tachyarrhythmias and paroxysmal atrial fibrillation. Whether the autonomic tone has a role in the initiation of paroxysmal atrial flutter has not been reported.
Holter electrocardiographic recording was used to investigate the changes in heart rate variability before the onset of paroxysmal atrial flutter.
A total of 12 patients with paroxysmal atrial flutter were analyzed. An increase in the normalized value of the low frequency (LF) component and the LF/high frequency (HF) ratio and a decrease in the normalized value of the HF component began at 6 min before the onset of episodes of paroxysmal atrial flutter, which indicated that sympathovagal balance had shifted to more sympathetic predominance.
An increase in sympathetic modulation or vagal withdrawal, or both, may facilitate the initiation of atrial flutter.
本研究旨在探讨阵发性心房扑动发作前自主神经张力的变化。
心脏自主神经张力的突然改变是室性快速性心律失常和阵发性心房颤动发病机制中的一个重要起始因素。自主神经张力在阵发性心房扑动的起始中是否起作用尚未见报道。
采用动态心电图记录来研究阵发性心房扑动发作前心率变异性的变化。
共分析了12例阵发性心房扑动患者。阵发性心房扑动发作前6分钟开始，低频（LF）成分的标准化值和LF/高频（HF）比值增加，HF成分的标准化值降低，这表明交感迷走神经平衡已转向以交感神经占优势。
交感神经调节增加或迷走神经撤离，或两者兼而有之，可能促进心房扑动的起始。
