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即将发生的反常栓塞

Impending paradoxical embolism.

作者信息

Meacham R R, Headley A S, Bronze M S, Lewis J B, Rester M M

机构信息

University of Tennessee-Memphis Lung Research Program and the Division of General Internal Medicine, USA.

出版信息

Arch Intern Med. 1998 Mar 9;158(5):438-48. doi: 10.1001/archinte.158.5.438.

Abstract

The advent of echocardiography has led to the more frequent discovery of impending paradoxical embolism. Paradoxical embolism should be considered whenever there is an arterial embolism from an unidentified source in the presence of a concomitant venous thromboembolic phenomenon. Patients with paradoxical embolism present with neurological abnormalities or features suggesting arterial embolism. Annually, paradoxical embolism may account for up to 47,000 strokes in the United States, and a patent foramen ovale has been reported in up to 35% of the normal population. Events that give rise to pulmonary hypertension may result in a right-to-left shunt through a patent foramen ovale allowing a venous thromboembolism access to the arterial circulation. Herein we report a case of impending paradoxical embolism and review the pertinent literature.

摘要

超声心动图的出现使得即将发生的反常栓塞被更频繁地发现。当存在不明来源的动脉栓塞且伴有静脉血栓栓塞现象时,应考虑反常栓塞。反常栓塞患者表现为神经功能异常或提示动脉栓塞的特征。在美国,每年反常栓塞可能导致多达47,000例中风,据报道,高达35%的正常人群存在卵圆孔未闭。导致肺动脉高压的事件可能会通过卵圆孔未闭形成右向左分流,使静脉血栓栓塞进入动脉循环。在此,我们报告一例即将发生的反常栓塞病例并复习相关文献。

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