Olsen D B, Kolff J, Lawson J, Stellwag F, Ceccarelli V, Fukumasu H, Kolff W J
Trans Am Soc Artif Intern Organs. 1976;22:468-77.
The natural aortic and pulmonary artery valves can be saved with excision of the ventricles and inflow valves. These valves remain functional and unaltered with implantation of an artificial heart, when pumped for 96 and 122 days. The capacity of the artificial heart to meet the physiological needs of the animal, during exercise and body growth, over 3 and 4 mos has been documented. All of the parameters monitored in 2 experiments for 3 mos (and continuing) and 4 mos clearly demonstrates the efficacy of meeting the cardiac needs with an artificial heart.
通过切除心室和流入瓣膜,可以保留天然的主动脉瓣和肺动脉瓣。当人工心脏泵血96天和122天时,这些瓣膜在植入人工心脏后仍保持功能且未发生改变。已经有文献记载,在3至4个月的时间里,人工心脏在动物运动和身体生长过程中满足其生理需求的能力。在两项实验中,对3个月(并持续进行)和4个月的所有监测参数进行分析,清楚地证明了人工心脏满足心脏需求的有效性。