Gurbel P A, Serebruany V L
Union Memorial Hospital, Baltimore, Maryland 21218, USA.
Am J Cardiol. 1998 Mar 15;81(6):772-5. doi: 10.1016/s0002-9149(97)01035-7.
Twenty-three patients enrolled in th GUSTO-III study underwent serial measurements of soluble vascular cell adhesion molecule-1 (VCAM-1) and E-selectin by enzyme-linked immunosorbent assay at prespecified time intervals. Soluble VCAM-1, but not E-selectin levels, were increased in patients with acute myocardial infarction, indicating that VCAM-1 may serve as a marker of increased endothelial activation in acute myocardial infarction.
23名参与GUSTO-III研究的患者在预先设定的时间间隔，通过酶联免疫吸附测定法对可溶性血管细胞黏附分子-1（VCAM-1）和E-选择素进行了系列测量。急性心肌梗死患者的可溶性VCAM-1水平升高，而E-选择素水平未升高，这表明VCAM-1可能是急性心肌梗死中内皮激活增加的一个标志物。
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