[Cytologic analysis of the secretory epithelium of submaxillary salivary glands hypertrophied by repeated amputation of the lower incisors in rats].

Repeated amputation of the lower incisor in August line rats induced hypertrophy of the submandibular and sublingual salivary glands. This was true hypertrophy accompanied by hypertrophy of the structural units (acini, cells, nuclei). Cell hypertrophy depended on the hypertrophy of the organellae and the accumulation of secretory materials in the cells. Hypertrophy of the nuclei of acinar cells was conditioned by polyploidisation. Polyploidisation and the changes in the cell ulctrastructure in the submandibular salivary glands pointed to the increase in the functional activity of the organ.