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[含碘制剂抗菌效果的定量评估方法]

[Method of quantitative assessment of antimicrobial effects of iodine-containing preparations].

作者信息

Livitskiĭ V I, Pyshchev A I, Martynenko L D

出版信息

Klin Lab Diagn. 1998 Jan(1):44-6.

PMID:9532902
Abstract

Iodine-containing preparations were studied by UV spectral analysis. Water-soluble composition of 1,3-diethylbenzimidasolium triiodide is inactivated in the presence of meat-peptone broth. Dissolving of these preparations in a mixture of acetone and stearic acid does not change the physicochemical properties or impair the antibacterial effect. A high antibacterial effect of 12 iodine-containing compounds has been demonstrated: 15-min exposure suppressed the growth of bacteria at the minimal concentration of 0.1-1.0 microgram/ml.

摘要

通过紫外光谱分析对含碘制剂进行了研究。1,3 - 二乙基苯并咪唑三碘化物的水溶性成分在肉蛋白胨肉汤存在下会失活。将这些制剂溶解在丙酮和硬脂酸的混合物中不会改变其物理化学性质,也不会削弱其抗菌效果。已证明12种含碘化合物具有高抗菌效果:在最低浓度为0.1 - 1.0微克/毫升时,15分钟的暴露可抑制细菌生长。

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