Dopamine synthesizing enzymes in paraventricular hypothalamic neurons of the human and monkey (Macaca fuscata).
作者信息
Kitahama K, Ikemoto K, Jouvet A, Nagatsu I, Geffard M, Okamura H, Pearson J
机构信息
Département de Médecine Expérimentale, INSERM U480, Faculté de Médecine, Université Claude Bernard, Lyon, France.
出版信息
Neurosci Lett. 1998 Feb 27;243(1-3):1-4. doi: 10.1016/s0304-3940(98)00057-3.
PMID:9535098
Abstract
Using immunohistochemistry, we demonstrated that paraventricular hypothalamic neurons immunoreactive for tyrosine hydroxylase (TH) were not immunopositive for the second step catecholamine synthesizing enzyme L-amino acid decarboxylase (AADC) in the human and monkey Macaca fuscata. In the latter species, they were not immunoreactive for dopamine. It is most likely that primate paraventricular TH-containing neurons do not synthesize dopamine.
摘要
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