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鞘内注射普通利多卡因引起的短暂性神经根刺激

Transient radicular irritation with intrathecal plain lignocaine.

作者信息

Henderson D J, Faccenda K A, Morrison L M

机构信息

Dept. of Anaesthetics, St. John's Hospital at Howden, Livingston, UK.

出版信息

Acta Anaesthesiol Scand. 1998 Mar;42(3):376-8. doi: 10.1111/j.1399-6576.1998.tb04932.x.

Abstract

BACKGROUND

The aetiology of the syndrome known as transient radicular irritation (TRI) has generated much interest.

METHOD

A 50-year-old woman had right knee arthroscopy performed under spinal anaesthesia with 1% plain lignocaine.

RESULT

At home, on the night of the procedure, she was woken by severe, bilateral cramp-like pain in both buttocks radiating to her thighs. Neurological examination of her lower limbs, the next morning, was entirely normal. The pain lasted for 36 h and a full recovery was made.

CONCLUSION

This case of transient radicular irritation occurred in a patient given 40 mg of subarachnoid lignocaine (the lowest dose of isobaric preservative-free lignocaine reported thus far that has been associated with these symptoms). Her operation was performed in the supine position. The lack of confounding factors (hyperbaricity, high concentration solution, preservatives, lithotomy position) suggests lignocaine as a possible cause, yet current theories do not fully explain the aetiology of transient radicular irritation. Results from large-scale epidemiological studies will hopefully provide insight into the cause of this problem.

摘要

背景

被称为短暂性神经根刺激(TRI)综合征的病因引发了诸多关注。

方法

一名50岁女性在蛛网膜下腔麻醉下使用1%普通利多卡因进行了右膝关节镜检查。

结果

术后当晚在家中,她被双侧臀部严重的痉挛样疼痛惊醒,疼痛放射至大腿。次日早晨对其下肢进行的神经学检查完全正常。疼痛持续了36小时,随后完全康复。

结论

该例短暂性神经根刺激发生在一名接受了40毫克蛛网膜下腔利多卡因的患者身上(这是迄今为止报道的与这些症状相关的最低剂量的等比重无防腐剂利多卡因)。她的手术是在仰卧位进行的。缺乏混杂因素(高比重、高浓度溶液、防腐剂、截石位)提示利多卡因可能是病因,但目前的理论并不能完全解释短暂性神经根刺激的病因。大规模流行病学研究的结果有望为该问题的病因提供见解。

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