Pellicano M, Zullo F, Catizone C, Guida F, Catizone F, Nappi C
Department of Obstetrics and Gynecology, University of Naples Federico II, Italy.
Ultrasound Obstet Gynecol. 1998 Feb;11(2):144-6. doi: 10.1046/j.1469-0705.1998.11020144.x.
Congenital granular epulis is a benign tumor that has rarely been diagnosed prenatally, although there have been numerous reports on its postnatal diagnosis. We report a case of large granular epulis diagnosed at 31 weeks' gestation in a woman whose previous anomaly scan had been normal. The lesion was 2.5 cm in diameter, pedunculated, and arose from the maxilla. It was completely surgically removed following preterm vaginal birth and histologically examined. The tumor did not prevent deglutition of the amniotic fluid and did not interfere with feeding or respiration, but prevented complete closure of the lips. We discuss the fetal management and the theories of histogenesis, and highlight the importance of early diagnosis and treatment.
先天性颗粒性牙龈瘤是一种良性肿瘤，产前很少被诊断出来，尽管有许多关于其产后诊断的报道。我们报告一例在妊娠31周时诊断出的巨大颗粒性牙龈瘤病例，该孕妇之前的超声检查未见异常。病变直径为2.5厘米，有蒂，起源于上颌骨。早产经阴道分娩后，该病变被完全手术切除并进行了组织学检查。该肿瘤未妨碍羊水吞咽，也未干扰喂养或呼吸，但导致嘴唇无法完全闭合。我们讨论了胎儿管理和组织发生学理论，并强调了早期诊断和治疗的重要性。
