Stuhrmann M, Roefke C, Jahnke T, Cramer B M
Radiologische Klinik, Universität Witten-Herdecke.
Rofo. 1998 Mar;168(3):258-63. doi: 10.1055/s-2007-1015122.
The aim of this prospective study was to evaluate the potentials and limits of Doppler waveform analysis of intrarenal vessels in patients with suspected renal artery stenosis.
In a three-year study we compared our colour Doppler results of 111 patients with the angiography results. Evaluated parameters were acceleration time (AT), acceleration index (AI) and early systolic peak (ESP).
The sensitivity of severe stenoses (> or = 70%) was 89%. In moderate stenoses (50-70%) it was possible to increase the sensitivity from 56% to 76% if a comparison with the contralateral side was included. The specificity was 91%. Causes for limited sensitivity and specificity were poor examination conditions, stenoses of accessory renal arteries and moderate stenoses as well as diffuse non-stenosing lesions.
In comparison with angiography, the diagnostic value of Doppler waveform analysis in the detection of renal artery stenoses has specific limitations. In significant stenoses, however, additional valuable haemodynamic information, useful for PTA, can be obtained by this easy and accessible method.
这项前瞻性研究的目的是评估对疑似肾动脉狭窄患者进行肾内血管多普勒波形分析的潜力和局限性。
在一项为期三年的研究中，我们将111例患者的彩色多普勒检查结果与血管造影结果进行了比较。评估参数包括加速时间（AT）、加速指数（AI）和收缩早期峰值（ESP）。
重度狭窄（≥70%）的敏感性为89%。在中度狭窄（50%-70%）时，如果与对侧进行比较，敏感性可从56%提高到76%。特异性为91%。敏感性和特异性受限的原因包括检查条件不佳、副肾动脉狭窄、中度狭窄以及弥漫性非狭窄性病变。
与血管造影相比，多普勒波形分析在检测肾动脉狭窄方面的诊断价值存在特定局限性。然而，对于明显狭窄，通过这种简单且可及的方法可以获得对经皮腔内血管成形术（PTA）有用的额外有价值的血流动力学信息。
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