鸟类肝脏中卵黄蛋白原合成的激素调控。
Hormonal control of vitellogenin synthesis in avian liver.
作者信息
Gruber M, Bos E S, Ab G
出版信息
Mol Cell Endocrinol. 1976 Jun-Jul;5(1-2):41-50. doi: 10.1016/0303-7207(76)90069-1.
PMID:955247
Abstract
Estradiol induces the synthesis of vitellogenin in the avian liver. We describe the precursor-product relationship between vitellogenin and the yolk proteins phosvitin and lipovitellin. The high rate of vitellogenin synthesis is a consequence of the accumulation of a stable messenger RNA. We suggest that estradiol acts at the level of the genome by opening a hitherto non-transcribed gene.
摘要
雌二醇可诱导鸟类肝脏中卵黄蛋白原的合成。我们描述了卵黄蛋白原与卵黄磷蛋白和脂卵黄蛋白之间的前体-产物关系。卵黄蛋白原的高合成率是稳定信使核糖核酸积累的结果。我们认为，雌二醇通过开启一个此前未转录的基因在基因组水平发挥作用。
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