Singh J P, Musialek P, Sleight P, Davey P, Marinho M, Hart G
Department of Cardiovascular Medicine, John Radcliffe Hospital, University of Oxford, United Kingdom.
Am J Cardiol. 1998 Apr 1;81(7):924-6. doi: 10.1016/s0002-9149(98)00022-8.
In subjects with a recent acute myocardial infarction, the hour immediately following awakening is associated with an abrupt exaggeration of heart rate-dependent changes and variability of the QT interval. Beta blockers were observed to blunt these waking hour changes.
在近期发生急性心肌梗死的患者中，醒来后的首个小时与心率依赖性变化及QT间期变异性的突然增大有关。观察发现，β受体阻滞剂可减弱这些清醒时段的变化。
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