Suma H, Isomura T, Horii T, Ichihara T, Sato T, Nishimi M, Fujisaki H, Ukawa T, Iwahashi K
Department of Cardiovascular Surgery, Shonan-Kamakura General Hospital, Kanagawa.
J Cardiol. 1998 Mar;31(3):165-70.
Endoventricular circular patch plasty (Dor operation) was used to treat end-stage dilated ischemic cardiomyopathy in 13 patients from January to December, 1997. There were 10 men and three women aged from 57 to 78 years (mean 63 years). Single, double, triple and left main trunk coronary disease was present in one, two, eight and two patients, respectively. Mean ejection fraction was 22% (6-30%) and signs of congestive heart failure were clear in all patients [New York Heart Association (NYHA) class III in eight patients and class IV in five patients]. Angina pectoris was present in five patients. Six patients had associated significant mitral regurgitation. Coronary artery bypass grafting (mean 3.2 grafts) was used in 11 patients and mitral valve reconstruction was performed in 6 patients (4: replacement and 2: repair) combined with akinetic area exclusion by the Dor technique. All patients were successfully weaned from cardiopulmonary bypass without mechanical support and no perioperative death occurred. Three patients died in hospital at 1-2 postoperative months due to pneumonia, stroke and heart failure, respectively. Two patients died during the late period due to stroke and sudden death. Among the eight survivors, six patients were in NYHA class I-II and two patients in class III. Ejection fraction increased from 22% to 36%, end-diastolic and systolic volume indices decreased from 168 +/- 58 to 123 +/- 39 ml/m2 and from 131 +/- 60 to 81 +/- 33 ml/m2, respectively. Pulmonary capillary wedge pressure decreased from 19 +/- 10 to 14 +/- 5 mmHg. The Dor procedure is an effective surgical alternative for patients with end-stage ischemic cardiomyopathy who are considered to be candidates for cardiac transplantation.
1997年1月至12月,采用心室内环形补片成形术(Dor手术)治疗13例终末期扩张型缺血性心肌病患者。其中男性10例,女性3例,年龄57至78岁(平均63岁)。单支、双支、三支及左主干冠状动脉病变分别见于1例、2例、8例和2例患者。平均射血分数为22%(6% - 30%),所有患者均有明显的充血性心力衰竭体征[纽约心脏协会(NYHA)分级:Ⅲ级8例,Ⅳ级5例]。5例患者有胸痛症状。6例患者合并有严重二尖瓣反流。11例患者行冠状动脉旁路移植术(平均3.2支血管),6例患者行二尖瓣重建术(4例置换,2例修复),同时采用Dor技术排除运动减弱区域。所有患者均成功脱离体外循环,无需机械支持,无围手术期死亡。3例患者分别于术后1 - 2个月因肺炎、中风和心力衰竭死于医院。2例患者在后期因中风和猝死死亡。8例幸存者中,6例NYHA分级为Ⅰ - Ⅱ级,2例为Ⅲ级。射血分数从22%提高到36%,舒张末期和收缩末期容积指数分别从168±58降至123±39 ml/m²和从131±60降至81±33 ml/m²。肺毛细血管楔压从19±10降至14±5 mmHg。对于被认为是心脏移植候选者的终末期缺血性心肌病患者,Dor手术是一种有效的手术选择。