Barnard M, Chalvardjian A
Department of Pathology, St. Michael's Hospital and University of Toronto, Ontario, Canada.
Am J Dermatopathol. 1998 Apr;20(2):185-8. doi: 10.1097/00000372-199804000-00015.
Malakoplakia is an uncommon granulomatous lesion that afflicts predominantly immunocompromised individuals but is extremely rare in acquired immunodeficiency syndrome (AIDS). We report a case of cutaneous malakoplakia in an AIDS patient that presented as a banal right axillary abscess which resolved after excision and drainage. The rarity of malakoplakia in AIDS may be due to a relative or selective preservation of antimicrobial function of monocytes. Malakoplakia is distinguished from other inflammatory or neoplastic lesions by the presence of Michaelis-Gutmann bodies. A correct diagnosis is usually made only after biopsy and is an indication to use antimicrobial agents with adequate cellular penetration and concentration.
软斑病是一种罕见的肉芽肿性病变，主要累及免疫功能低下的个体，但在获得性免疫缺陷综合征（艾滋病）中极为罕见。我们报告一例艾滋病患者发生的皮肤软斑病，表现为一个普通的右腋窝脓肿，切除引流后痊愈。软斑病在艾滋病中罕见可能是由于单核细胞的抗菌功能相对或选择性保留。软斑病通过存在迈克尔is-古特曼小体与其他炎症或肿瘤性病变相鉴别。通常只有在活检后才能做出正确诊断，这是使用具有足够细胞穿透力和浓度的抗菌药物的指征。
