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炎症介导的骨质疏松症(IMO)对兔骨骼钙/磷比值以及骨和皮肤胶原蛋白结构的影响。

The effects of inflammation-mediated osteoporosis (IMO) on the skeletal Ca/P ratio and on the structure of rabbit bone and skin collagen.

作者信息

Fountos G, Kounadi E, Tzaphlidou M, Yasumura S, Glaros D

机构信息

Department of Medical Physics, Medical School, University of Ioannina, Greece.

出版信息

Appl Radiat Isot. 1998 May-Jun;49(5-6):657-9. doi: 10.1016/s0969-8043(97)00086-9.

Abstract

The relationships between the skeletal Ca/P ratio (used as an index of bone quality) and structural changes in the bone and skin was studied in inflammatory mediated osteoporosis (IMO). The bone Ca/P ratio in IMO rabbits was significantly lower than in controls. Also, severe alterations were detected at the ultrastructural level in bone and skin collagen fibrils from IMO rabbits.

摘要

在炎症介导的骨质疏松症(IMO)中,研究了骨骼钙磷比(用作骨质量指标)与骨骼和皮肤结构变化之间的关系。IMO兔的骨钙磷比显著低于对照组。此外,在IMO兔的骨骼和皮肤胶原纤维的超微结构水平上检测到严重改变。

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