Tsuang M T
Harvard Medical School Department of Psychiatry, Massachusetts Mental Health Center, Boston 02115, USA.
J Biomed Sci. 1998;5(1):28-30. doi: 10.1007/BF02253353.
Evidence for genetic factors in schizophrenia is reviewed with regard to family, twin and adoption studies, and recent advances in molecular genetic technology are applied to explore possible gene loci susceptible to schizophrenia. Application of neuropsychological and neuroimaging methodologies are also reviewed with an aim to develop criteria for defining phenotypes for genetic studies.
本文综述了精神分裂症遗传因素在家族、双生子和收养研究方面的证据,并应用分子遗传技术的最新进展来探索可能易患精神分裂症的基因位点。还综述了神经心理学和神经影像学方法的应用,目的是制定遗传研究中定义表型的标准。