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[根治性D2淋巴结清扫胃切除术——胃癌的有效且经济规范的治疗方法]

[Gastrectomy with radical D2 lymph node excision--effective and economically standardized therapy of adenocarcinoma of the stomach].

作者信息

Schmid A, Thybusch A, Henne-Bruns D, Kremer B

机构信息

Klinik für Allgemeine Chirurgie und Thoraxchirurgie, Kliniken der Christian-Albrechts-Universität Kiel.

出版信息

Langenbecks Arch Chir Suppl Kongressbd. 1997;114:1066-8.

PMID:9574334
Abstract

In a retrospective single center study, the impact of radical D2-lymph adenectomy and splenectomy on operativ course, morbidity, mortality and long-term survival, in 243 patients who underwent radical surgical therapy for gastric cancer, was analyzed. D2-lymph node dissection during gastrectomy or gastric resection did not influence blood loss, artificial respiration time, ICU days or surgical morbidity, whereas splenectomy correlated with a higher hospital mortality, leakage and abscess rate. Due to routinely performed D2-lymphadenectomy long term survival rate (5 years) was 40.6% for all (in detail: 96% in stage IA; 68.5%/IB; 61.2%/II; 35.8%/IIIA; 17.3%IIIB; and 2.6% in stage IV and 58.1% for curative resected patients.

摘要

在一项回顾性单中心研究中,分析了243例行胃癌根治性手术治疗患者的D2根治性淋巴结清扫术和脾切除术对手术过程、发病率、死亡率及长期生存的影响。胃切除术或胃切除术中的D2淋巴结清扫术不影响失血量、人工呼吸时间、重症监护病房(ICU)住院天数或手术发病率,而脾切除术与较高的医院死亡率、渗漏及脓肿发生率相关。由于常规进行D2淋巴结清扫术,所有患者的长期生存率(5年)为40.6%(具体为:IA期96%;IB期68.5%;II期61.2%;IIIA期35.8%;IIIB期17.3%;IV期2.6%),根治性切除患者为58.1%。

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