Büsing M, Martin D, Schulz T, Heimes M, Klempnauer J, Kozuschek W
Chirurg. 1998 Mar;69(3):291-7. doi: 10.1007/s001040050415.
The experience worldwide with pancreas transplantation includes more than 9000 cases. In the most popular patient group (simultaneous pancreas-kidney transplantation, SPK) the graft-function rate at 1 year now reaches more than 80%. More than 90% of all pancreas transplants were performed using the bladder-drainage technique (BD) with systemic venous anastomosis. Late problems with the BD require enteric conversion in 10-20% in the long term. In the present study we report the results of 40 SPK using the BD (n = 20) and enteric drainage (ED) techniques (n = 20). After 3 months, the patients pancreas and kidney survival rates in the BD group were 100, 95 and 100% and in the ED group 100, 100 and 100%, respectively. No anastomosis leakage occurred in either group. In two cases of the ED group the pancreas grafts were drained portal venously via the superior mesenteric vein without surgical complications. With growing experience, excellent SPK results can be reached with both the BD and ED techniques.
全球胰腺移植的经验包括超过9000例病例。在最常见的患者群体(胰肾联合移植,SPK)中,1年时移植物功能率目前达到80%以上。所有胰腺移植中超过90%采用膀胱引流技术(BD)并进行全身静脉吻合。BD的晚期问题长期来看需要10%至20%的患者进行肠道改道。在本研究中,我们报告了40例采用BD技术(n = 20)和肠道引流(ED)技术(n = 20)的SPK结果。3个月后,BD组患者的胰腺和肾脏存活率分别为100%、95%和100%,ED组分别为100%、100%和100%。两组均未发生吻合口漏。在ED组的2例患者中,胰腺移植物通过肠系膜上静脉进行门静脉引流,无手术并发症。随着经验的积累,BD和ED技术均可取得出色的SPK结果。