VanderArk C R, Reynolds E W, Kahn D R, Tullett G
J Thorac Cardiovasc Surg. 1976 Sep;72(3):464-7.
Quinidine syncope is an unpredictable side effect of quinidine administrateion which has a mortality rate of 11.5 per cent when managed with conventional drugs and direct-current countershock. In 2 patients with quindine syncope, the arrhythmias were effectively controlled within 30 minutes following the slow infusion of 150 mg. of bretylium tosylate. This control is contrasted with 2 cases managed in the conventional manner. Bretylium tosylate is a quaternary amine with unique antifibrillatory properties and appears to have a significant role in the management of these arrhylmias.
奎尼丁晕厥是奎尼丁给药后一种不可预测的副作用，采用传统药物和直流电除颤治疗时死亡率为11.5%。在2例奎尼丁晕厥患者中，缓慢输注150毫克甲苯磺酸溴苄铵后30分钟内心律失常得到有效控制。这一情况与2例采用传统方式治疗的病例形成对比。甲苯磺酸溴苄铵是一种具有独特抗纤颤特性的季铵盐，似乎在这些心律失常的治疗中具有重要作用。
