Delbrouck C, Kampouridis S, Chantrain G
Department of Ear, Nose, Throat, Head and Neck Surgery, Université Libre de Bruxelles, Belgium.
Acta Otorhinolaryngol Belg. 1998;52(1):29-36.
The epidemic form of Kaposi's sarcoma is associated with human immunodeficiency virus infection. Cutaneous and mucosal manifestations are frequently reported in the ENT sphere, mostly involving the oral cavity. The external and middle ear are only rarely concerned with only one case of a mastoid lesion without extension to the external auditory canal (EAC) being reported to this day. The present article describes the first case of involvement of the EAC with extension to adjacent structures. This patient presented other Kaposi lesions and had been treated by systemic hormonal therapy. Thereafter local injection of a cytotoxic agent was given without effect. Finally, radiotherapy resulted in a 50% regression of the tumour mass. The epidemiologic factors and therapeutic modalities with their results are described.
卡波西肉瘤的流行形式与人类免疫缺陷病毒感染有关。皮肤和黏膜表现常在耳鼻喉领域出现,主要累及口腔。外耳道和中耳很少受累,至今仅报道过1例乳突病变且未累及外耳道的病例。本文描述了首例累及外耳道并蔓延至相邻结构的病例。该患者还存在其他卡波西病变,曾接受全身激素治疗。此后局部注射细胞毒性药物但无效。最后,放疗使肿瘤肿块缩小了50%。文中描述了流行病学因素、治疗方式及其结果。