Shahmohammadi H R, Terato H, Asgarani E, Saito T, Fumamizu H, Ohyama Y, Gekko K, Ide H
Graduate Department of Gene Science, Faculty of Science, Hiroshima University, Higashi-Hiroshima, Japan.
Nucleic Acids Symp Ser. 1997(37):163-4.
High concentration salt effects on the structure and radiation-induced damages of DNA were studied to elucidate the biochemical mechanism of the resistance of halophilic H. salinarium against DNA damaging agents. High concentration of KCl did not induce significant conformational changes in H. salinarium chromosomal DNA, but exhibited an extensive protective effect on the radiation-induced single-strand breaks of plasmid DNA.
研究了高浓度盐对DNA结构和辐射诱导损伤的影响，以阐明嗜盐盐生盐杆菌对DNA损伤剂抗性的生化机制。高浓度的KCl不会诱导盐生盐杆菌染色体DNA发生显著的构象变化，但对辐射诱导的质粒DNA单链断裂具有广泛的保护作用。
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