Himeno H, Nameki N, Tadaki T, Sato M, Hanawa K, Fukushima M, Ishii M, Ushida C, Muto A
Department of Biology, Hirosaki University, Japan.
Nucleic Acids Symp Ser. 1997(37):185-6.
Here we show that Escherichia coli tmRNA (10Sa RNA) has a dual function both as an mRNA and as a tRNA in vitro. The function as a tRNA is prerequisite for the function as an mRNA. These observations strongly support the trans-translation hypothesis.
我们在此表明,大肠杆菌的转移信使核糖核酸(10S a RNA)在体外兼具信使核糖核酸和转运核糖核酸的双重功能。作为转运核糖核酸的功能是其作为信使核糖核酸功能的前提条件。这些观察结果有力地支持了反式翻译假说。