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[Neurobiology of erectile dysfunction in multiple sclerosis].

作者信息

Salinas Casado J, Vírseda Chamorro M, Samblás García R, Esteban Fuertes M, Aristizábal Agudelo J M, Delgado Martín J A, Blázquez Izquierdo J, Resel Estévez L

机构信息

Servicio de Urología, Hospital Universitario San Carlos, Universidad Complutense, Madrid, España.

出版信息

Arch Esp Urol. 1998 Mar;51(2):167-70.

PMID:9586316
Abstract

OBJECTIVE

To analyze the neurological alterations responsible for impotence in multiple sclerosis.

METHODS

We conducted a pharmacologic erection test and a neuroandrologic profile study in 11 patients with multiple sclerosis and impotence. This study consisted in: bulbocavernosus EMG, S2-S4 evoked potentials, somatosensory potentials of pudendal nerve, electromyography of cavernous smooth muscle (SPACE), sympathetic skin response (SSR) and cystometry.

RESULTS

The most frequent neurological lesion was complete suprasacral (7 cases; 64%) and parasympathetic (7 cases; 64%) lesions. The parasympathetic lesions were of the upper motor neuron type in 6 of the 7 cases (86%). Peripheral autonomic [sympathetic in 2 cases (18%); parasympathetic in 1 case (9%)] and pudendal lesions (3 cases; 27%) were also observed.

CONCLUSIONS

The main cause of impotence in multiple sclerosis could be ascribed to a suprasacral lesion. Some cases also present peripheral autonomic lesions.

摘要

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1
Bladder, bowel and sexual dysfunction in multiple sclerosis: management strategies.多发性硬化症中的膀胱、肠道及性功能障碍:管理策略
Drugs. 2003;63(2):153-66. doi: 10.2165/00003495-200363020-00003.
2
Neurogenic erectile dysfunction.神经源性勃起功能障碍
Clin Auton Res. 2001 Oct;11(5):285-94. doi: 10.1007/BF02332973.