Osterwalder P, Goehde S C, Stürmer J, Vetter W
Department für Innere Medizin, Medizinische Poliklinik, Universitätsspital Zürich.
Praxis (Bern 1994). 1998 Apr 1;87(14):483-90.
In a 67 year old patient with multiple cardiovascular risk factors a livedo reticularis, ischemic acral lesions as well as deterioration of renal function five weeks after cardiac catheterism and aorto-coronary bypass surgery led to suspicion of cholesterol embolism. Fundoscopy revealed cholesterol crystals in retinal vascular branches thus delivering important diagnostic information. Atheromatous lesions of the entire aorta and the ilio-femoral arteries were possible sources for embolism. The outcome was favorable. The lesions of the toes regressed and renal failure did not progress to dialysis. The diagnostic steps taken, the clinical picture of cholesterol embolism, the use of imaging and therapeutic options are discussed.
在一名有多种心血管危险因素的67岁患者中,心脏导管插入术和主动脉冠状动脉搭桥手术后五周出现网状青斑、缺血性肢端病变以及肾功能恶化,这引发了胆固醇栓塞的怀疑。眼底镜检查发现视网膜血管分支中有胆固醇结晶,从而提供了重要的诊断信息。整个主动脉和髂股动脉的动脉粥样硬化病变可能是栓塞的来源。结果是良好的。脚趾病变消退,肾衰竭未进展到需要透析的程度。文中讨论了所采取的诊断步骤、胆固醇栓塞的临床表现、影像学的应用及治疗选择。