角膜上皮与眼睛的紫外线防护
Corneal epithelium and UV-protection of the eye.
作者信息
Ringvold A
机构信息
University Eye Department, National Hospital Oslo, Norway.
出版信息
Acta Ophthalmol Scand. 1998 Apr;76(2):149-53. doi: 10.1034/j.1600-0420.1998.760205.x.
PURPOSE
To study UV-absorption and UV-induced fluorescence in the bovine corneal epithelium.
METHODS
Spectrophotometry and spectrofluorimetry.
RESULTS
The corneal epithelium absorbs UV-B radiation mainly owing to its content of protein, RNA, and ascorbate. Some of the absorbed energy is transformed to the less biotoxic UV-A radiation by fluorescence. RNA and ascorbate reduce tissue fluorescence.
CONCLUSIONS
The corneal epithelium acts as a UV-filter, protecting internal eye structures through three different mechanisms: (1) Absorption of UV-B roughly below 310 nm wavelength. (2) Fluorescence-mediated ray transformation to longer wavelengths. (3) Fluorescence reduction. The extremely high ascorbate concentration in the corneal epithelium has a key role in two of these processes.
目的
研究牛角膜上皮中的紫外线吸收和紫外线诱导的荧光。
方法
分光光度法和荧光分光光度法。
结果
角膜上皮吸收紫外线B辐射主要归因于其蛋白质、RNA和抗坏血酸盐的含量。一些吸收的能量通过荧光转化为生物毒性较小的紫外线A辐射。RNA和抗坏血酸盐会降低组织荧光。
结论
角膜上皮起到紫外线滤光器的作用，通过三种不同机制保护眼内结构：（1）吸收波长大致低于310nm的紫外线B。（2）荧光介导的光线转化为更长波长。（3）荧光减少。角膜上皮中极高的抗坏血酸盐浓度在其中两个过程中起关键作用。
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