使用带有协变量信息的冈珀茨模型对治愈率进行建模。
Modelling cure rates using the Gompertz model with covariate information.
作者信息
Gieser P W, Chang M N, Rao P V, Shuster J J, Pullen J
机构信息
Pediatric Oncology Group Statistical Office, Gainesville, FL 32601-3330, USA.
出版信息
Stat Med. 1998 Apr 30;17(8):831-9. doi: 10.1002/(sici)1097-0258(19980430)17:8<831::aid-sim790>3.0.co;2-g.
Abstract
We extend the modified Gompertz hazard function, first used by Cantor and Shuster for estimation of cure rates from pediatric clinical trials, by including covariate effects. The extended model provides a convenient method for estimation of the cure rate as a function of treatments and covariates.
摘要
我们扩展了修正的冈珀茨风险函数，该函数最初由坎托和舒斯特用于从儿科临床试验中估计治愈率，方法是纳入协变量效应。扩展模型提供了一种便捷的方法，可将治愈率估计为治疗和协变量的函数。
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