Miyake H, Tashiro S, Yogita S, Ishikawa M, Fukuda Y, Harada M, Wada D, Ito S, Yasuda M
First Department of Surgery, University of Tokushima School of Medicine, Japan.
J Med Invest. 1998 Feb;44(3-4):219-21.
Gilbert's syndrome is the common cause of non hemolytic unconjugated hyperbilirubinemia with a prevalance of 3-7%. Gilbert's syndrome may introduce a selection of potential liver donors from brain death patients. We present a case of living-related liver transplantation (LRLT) from a donor with Gilbert's syndrome. A 22-year-old woman had been diagnosed as having liver cirrhosis at the age of 5. She underwent liver transplantation with the donor's left lobe as the graft. The donor, who was the father of the patient, had been diagnosed with Gilbert's syndrome. Although the recipient was well until 11 months after surgery, she died of subacute fulminant hepatitis 16 months after surgery. However, it was clear that the liver with Gilbert's syndrome could be used as a graft of living-related liver transplantation for adult recipients.
吉尔伯特综合征是导致非溶血性未结合胆红素血症的常见原因,患病率为3%至7%。吉尔伯特综合征可能会从脑死亡患者中筛选出一批潜在的肝脏供体。我们报告一例来自患有吉尔伯特综合征供体的活体肝移植(LRLT)病例。一名22岁女性在5岁时被诊断为肝硬化。她接受了以供体左叶为移植物的肝移植手术。供体是患者的父亲,已被诊断患有吉尔伯特综合征。尽管受者术后11个月情况良好,但在术后16个月死于亚急性暴发性肝炎。然而,很明显,患有吉尔伯特综合征的肝脏可以作为成人受者活体肝移植的移植物。