[不同性质辐射诱导的DNA和染色质辐射损伤的生物物理建模]
[Biophysical modeling of radiation damage in DNA and chromatin induced by radiation of varying quality].
作者信息
Andreev S G, Khvostunov I K, Spitkovskiĭ D M, Talyzina T A
出版信息
Radiats Biol Radioecol. 1997 Jul-Aug;37(4):533-8.
PMID:9599608
Abstract
DNA double strand breaks in chromatin induced by high LET ionizing radiation are analysed on the basis of biophysical modelling and computer simulation. Theoretical and experimental data are presented arguing in favour of nonrandom clustered distribution of DNA double strand breaks in chromatin.
摘要
基于生物物理建模和计算机模拟，对高传能线密度电离辐射诱导的染色质中的DNA双链断裂进行了分析。给出了理论和实验数据，支持染色质中DNA双链断裂的非随机簇状分布。
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