Marseglia G L, Locatelli F
Department of Pediatrics, University of Pavia, IRCCS Policlinico San Matteo, Italy.
J Pediatr. 1998 May;132(5):898-900. doi: 10.1016/s0022-3476(98)70330-0.
Pure red cell aplasia (PRCA) is a rare complication of treatment with isoniazid mainly observed in adults. We report two siblings who had anemia caused by PRCA during administration of isoniazid. On discontinuation of isoniazid, the anemia resolved rapidly. PRCA should be considered as a possible cause of unexplained anemia during isoniazid therapy in children.
纯红细胞再生障碍性贫血（PRCA）是异烟肼治疗的一种罕见并发症，主要见于成人。我们报告了两名在服用异烟肼期间因PRCA导致贫血的兄弟姐妹。停用异烟肼后，贫血迅速缓解。在儿童异烟肼治疗期间，PRCA应被视为不明原因贫血的可能原因。
