Varas Lorenzo M J, Maluenda M D, Pou J M, Abad R, Turró J, Espinós J C
Servicio de Endoscopia Digestiva, Hospital General de Cataluña, Centro Médico Teknon, Barcelona.
Gastroenterol Hepatol. 1998 Mar;21(3):121-4.
Twenty-one consecutive patients with 24 possible submucosal lesions of the digestive tract were studied. Endoscopic ultrasonography (EUS) differentiated between 17 true positive submucosal tumors and 3 true negative extrinsic compressions. False positives were interpreted in 3 cases and in one patient no lesion was echoendoscopically observed (false negative). The sensitivity was 94%, the specificity 50% and the positive and negative predictive values were 82% and 75%, respectively. In conclusion, EUS may be the method of choice for the study of submucosal tumors since it allows visualization of the five layers of the wall of the digestive tract in which a tumor may originate, determination of its sonographic features, depth and exact size, in addition to the invasion of neighboring organs. Moreover, EUS may aid in collecting material for cytology and microscopy by fine needle aspiration puncture (FNAP) by EUS.
对21例连续患者的24处可能的消化道黏膜下病变进行了研究。内镜超声检查(EUS)鉴别出17例真正的黏膜下肿瘤阳性病例和3例真正的外源性压迫阴性病例。3例出现假阳性,1例患者经超声内镜未观察到病变(假阴性)。敏感性为94%,特异性为50%,阳性预测值和阴性预测值分别为82%和75%。总之,EUS可能是研究黏膜下肿瘤的首选方法,因为它可以显示消化道壁的五层结构,肿瘤可能起源于此,还能确定其超声特征、深度和确切大小,以及对邻近器官的侵犯情况。此外,EUS可通过超声内镜细针穿刺抽吸活检(FNAP)辅助采集细胞学和显微镜检查材料。