Obara M, Satoh H, Ohtsuka M, Ishikawa S, Ishikawa H, Fujiwara M, Kamma H, Hasegawa S
Department of Respiratory Medicine, University of Tsukuba.
Nihon Kokyuki Gakkai Zasshi. 1998 Jan;36(1):95-9.
A 46-year-old woman was admitted to our hospital with chest pain. Chest X-ray and CT revealed an anterior mediastinal mass as well as several small masses attached to the left chest wall. Thymoma was diagnosed by percutaneous biopsy. The serum level of anti-acetylcholine receptor antibody was 30.3 pmol/ml. At operation, the thymoma was found left in the anterior mediastinum, extending to the upper lobe of the lung. There were also numerous tumors of various size in the left parietal pleura. Thymectomy, partial resection of the upper lobe of the lung and pleurectomy were performed. One month later, she developed myasthenia gravis. After a complete remission of myasthenia gravis brought about by anti-choline esterase therapy, the patient was treated with irradiation. She has been well for more than five years after the operation but her serum anti-acetylcholine receptor antibody level is still higher than normal.
一名46岁女性因胸痛入院。胸部X线和CT检查发现前纵隔肿块以及附着于左胸壁的几个小肿块。经皮活检诊断为胸腺瘤。抗乙酰胆碱受体抗体血清水平为30.3 pmol/ml。手术中发现胸腺瘤位于前纵隔左侧，延伸至肺上叶。左壁层胸膜也有许多大小不一的肿瘤。进行了胸腺切除术、肺上叶部分切除术和胸膜切除术。一个月后，她患上了重症肌无力。在抗胆碱酯酶治疗使重症肌无力完全缓解后，患者接受了放疗。术后她状况良好已超过五年，但血清抗乙酰胆碱受体抗体水平仍高于正常。
