Gregory M J, Schwartz G J
Department of Pediatrics, University of Rochester, NY 14642, USA.
Semin Nephrol. 1998 May;18(3):317-29.
There is a wide variety of renal tubular disorders affecting children. Understanding the pathophysiology of each disease assists in the recognition and treatment of these diseases, which can have profound effects on a child's growth and development. We review some of the more common tubular disorders found in children, emphasizing those conditions in which recent advances have been made in understanding of the specific genetic or physiological defect responsible: Fanconi's syndrome, cystinuria, renal tubular acidosis, and the hypokalemic metabolic alkaloses. Current recommendations are presented for diagnosing and treating these conditions.
有多种影响儿童的肾小管疾病。了解每种疾病的病理生理学有助于识别和治疗这些疾病，因为它们会对儿童的生长发育产生深远影响。我们回顾一些儿童中较常见的肾小管疾病，重点关注在理解特定遗传或生理缺陷方面取得了最新进展的那些病症：范科尼综合征、胱氨酸尿症、肾小管酸中毒和低钾性代谢性碱中毒。本文给出了诊断和治疗这些病症的当前建议。
