Schröder R J, Hadijuana J, Hidajat N, Mäurer J, Venz S, Vogl T, Weber S, Felix R
Strahlenklinik und Poliklinik, Virchow-Klinikum, Medizinische Fakultät Humboldt-Universität zu Berlin.
Rofo. 1998 May;168(5):444-50. doi: 10.1055/s-2007-1015160.
Prospective comparison of plain and signal-enhanced frequency and amplitude-modulated colour Doppler ultrasound of intramammary tumours to evaluate new criteria for diagnostic analysis.
Frequency and amplitude-modulated colour Doppler examination with qualitative and quantitative analysis of 80 potentially malignant intramammary lesions were performed before and after application of d-galactose.
Signal-enhanced sonography revealed a typical vessel morphology of primary and recurrent breast cancer facilitating differential diagnosis. In 18 (frequency modulated US) or 16 (amplitude modulated US) of 51 carcinomas, the typical malignant vascularisation structure was sufficiently visible only after application of the signal enhancing agent. In 50% of the fibroadenomas, Doppler analysis of the vessels was possible only after application of d-galactose.
The application of d-galactose provides additional criteria for the differential diagnosis of breast lesions due to improved visualisation of the vascularisation structure.
对乳腺内肿瘤的普通及信号增强型调频和调幅彩色多普勒超声进行前瞻性比较，以评估诊断分析的新标准。
在应用d-半乳糖前后，对80个潜在恶性乳腺内病变进行调频和调幅彩色多普勒检查，并进行定性和定量分析。
信号增强超声显示原发性和复发性乳腺癌典型的血管形态，有助于鉴别诊断。在51例癌中，18例（调频超声）或16例（调幅超声）典型的恶性血管化结构仅在应用信号增强剂后才能充分显示。在50%的纤维腺瘤中，仅在应用d-半乳糖后才能对血管进行多普勒分析。
由于血管化结构的可视化得到改善，d-半乳糖的应用为乳腺病变的鉴别诊断提供了额外标准。
