Inagaki M, Yuasa K, Nakayama E, Kawazu T, Chikui T, Kanda S, Yoshikawa H, Nakamura S, Shinohara M
Department of Oral and Maxillofacial Radiology, Faculty of Dentistry, Kyushu University, Fukuoka, Japan.
Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 1998 May;85(5):613-8. doi: 10.1016/s1079-2104(98)90300-6.
Six patients with mucoepidermoid carcinoma in the mandible were studied with both panoramic radiography and computed tomography. Lesion shape and margin were evaluated on panoramic radiography, and bony expansion and cortical plate destruction were evaluated on computed tomography. In addition, a possible correlation among radiographic findings, histologic findings, and prognosis was investigated. Lesions found on panoramic radiography were classified into three types; each type pertained to two of the six patients. The lesion types were as follows: cystic, characterized by a large, cystic radiolucent area; rarefying, characterized by rarefying changes of the trabeculae; and infiltrative, characterized by a central ill-defined area of bony destruction. The results show that computed tomography is useful in the identification of tumor extent, bony expansion, and cortical plate destruction resulting from tumors. None of the patients whose lesions were of the cystic or rarefying type showed evidence of disease after surgery. In contrast, both of the patients whose lesions were of the infiltrative type died of their tumors. Histologic findings of the cystic and rarefying types showed tumors that were well-differentiated or moderately well-differentiated, whereas findings of the infiltrative type showed poorly differentiated tumors. Radiographic findings correlated with histologic findings and prognosis of mucoepidermoid carcinoma in the mandible in this limited series.
对6例下颌骨黏液表皮样癌患者进行了全景X线摄影和计算机断层扫描研究。在全景X线摄影上评估病变的形状和边缘，在计算机断层扫描上评估骨质膨胀和皮质骨板破坏情况。此外，还研究了影像学表现、组织学表现与预后之间可能存在的相关性。在全景X线摄影上发现的病变分为三种类型；每种类型各有2例患者。病变类型如下：囊性，其特征为一个大的、囊性的透光区；骨质稀疏型，其特征为小梁的骨质稀疏改变；浸润型，其特征为中央边界不清的骨质破坏区。结果表明，计算机断层扫描有助于识别肿瘤范围、骨质膨胀以及肿瘤导致的皮质骨板破坏。病变为囊性或骨质稀疏型的患者术后均未显示疾病迹象。相比之下，病变为浸润型的2例患者均死于肿瘤。囊性和骨质稀疏型的组织学表现显示肿瘤为高分化或中分化，而浸润型的表现显示为低分化肿瘤。在这个有限的系列研究中，下颌骨黏液表皮样癌的影像学表现与组织学表现及预后相关。
