Viso P, Offenstadt G, Salem C, Amstutz P h
Ann Med Interne (Paris). 1976 Mar;127(3):215-23.
Spontaneous adrenal haemorrhages are rare but non exceptional. They mainly occur in elderly men (mean age: 61 years). The main risk factors are: anticoagulant therapy (prescribed for myocardial infarction, occlusive vascular ou thromboembolic disease), hypertension and chronic respiratory insufficiency, as in the present case. The clinical picture is one of abdominal of lumbar pain with abdominal distension, circulatory collapse, often delayed and sometimes preceeded by an hypertensive bout, quite often fever with leucocytosis. Hyponatraemia and hyperkalaemia, are not constant features. The diagnosis is often not made until laparotomy, and it even can be missed there. In fact, plasma cortisol level or, if unavailable, urinary corticosteroid measurements are the best diagnostic procedures, permitting adequate therapy and giving best chances of survival. They must always be made in a patient with abdominal signs falling into one of the above mentioned etiologic categories.
自发性肾上腺出血虽罕见但并非不常见。主要发生于老年男性(平均年龄:61岁)。主要危险因素有:抗凝治疗(用于心肌梗死、闭塞性血管或血栓栓塞性疾病)、高血压和慢性呼吸功能不全,如本例。临床表现为伴有腹胀的腹痛或腰痛、循环衰竭,常出现较晚,有时之前有高血压发作,常伴有发热和白细胞增多。低钠血症和高钾血症并非恒定特征。诊断往往在剖腹手术时才做出,甚至在手术中也可能漏诊。事实上,血浆皮质醇水平测定,或者在无法进行此项检测时,测定尿皮质类固醇,是最佳诊断方法,可实现适当治疗并提供最佳生存机会。对于有腹部体征且属于上述病因分类之一的患者,必须始终进行这些检测。