Inberg M V, Arola M, Arstila M, Havia T, Laaksonen V, Satokari K, Wegelius U, Vänttinen E
Ann Chir Gynaecol. 1976;65(2):104-9.
During a four-year period, aortic or mitral valve replacements with the Björk-Shiley tilting disc valve were performed in 114 cases. The series comprises 75 aortic, 34 mitral and 5 double valve replacements. In the aortic valve group (AVR) concomitant resection of the ascending aorta (cystic medial necrosis aneurysm)) was carried out in 5 cases, aortocoronary bypass in 2 cases and closure of a VSD in one case. Antibiotic prophylaxis and postoperative anticoagulant treatment were used routinely. The hospital mortality rates were6 8.0% in the AVR-group (single aortic valve mortality 7.1 %), 8.8% in the MVR-group and 60% in the double valve group. Late mortality in the AVR-group was 2.8%. There were no late thromboembolic complications in this group. Aortography showed grade II--III regurgitation (paravalvular leaks) in 15 % of the cases. In the MVR-group the late mortality was 9.7%. One patient died because of malfunction (thrombosis) of the prosthesis. The thrombotic complication was obviously caused by discontinuation of anticoagulant therapy. The clinically estimated functional capacity NYHA classification) improved considerably, especially in the MVR-group.
在四年期间，对114例患者实施了使用Björk-Shiley倾斜碟瓣的主动脉瓣或二尖瓣置换术。该系列包括75例主动脉瓣置换、34例二尖瓣置换和5例双瓣置换。在主动脉瓣置换组（AVR）中，5例患者同时进行了升主动脉切除（囊性中层坏死性动脉瘤），2例进行了主动脉冠状动脉搭桥术，1例进行了室间隔缺损闭合术。常规使用抗生素预防和术后抗凝治疗。AVR组的医院死亡率为8.0%（单纯主动脉瓣死亡率为7.1%），MVR组为8.8%，双瓣组为60%。AVR组的晚期死亡率为2.8%。该组无晚期血栓栓塞并发症。主动脉造影显示15%的病例存在II - III级反流（瓣周漏）。在MVR组中，晚期死亡率为9.7%。1例患者因人工瓣膜功能障碍（血栓形成）死亡。血栓形成并发症显然是由于抗凝治疗中断所致。临床评估的功能能力（纽约心脏协会分级）有显著改善，尤其是在MVR组。
