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肾移植患者发生默克尔细胞癌:发病率增加?

Merkel cell carcinoma in a renal transplant patient: increased incidence?

作者信息

Williams R H, Morgan M B, Mathieson I M, Rabb H

机构信息

Department of Pathology, University of South Florida College of Medicine, James A. Haley Veterans Administration Hospital, Tampa 33612, USA.

出版信息

Transplantation. 1998 May 27;65(10):1396-7. doi: 10.1097/00007890-199805270-00019.

Abstract

The identification of malignancies associated with transplantation has led to enhanced vigilance and care in these patients, as well as insight into the pathogenesis of select malignancies. We report a case of Merkel cell carcinoma, an uncommon cutaneous malignancy of neuroendocrine origin, diagnosed in a 65-year-old Caucasian man 6 years after renal transplantation. While it is well known that transplant patients are at increased risk for squamous cell carcinomas of the skin, other types may also have an increased frequency. We suggest that Merkel cell carcinoma could have an increased incidence in the transplant population.

摘要

与移植相关的恶性肿瘤的识别,提高了对这些患者的警惕性和护理水平,也为某些恶性肿瘤的发病机制提供了深入了解。我们报告一例默克尔细胞癌,这是一种罕见的神经内分泌起源的皮肤恶性肿瘤,在一名65岁的白人男性肾移植6年后被诊断出来。虽然众所周知,移植患者患皮肤鳞状细胞癌的风险增加,但其他类型的癌症发病率也可能增加。我们认为,默克尔细胞癌在移植人群中的发病率可能会增加。

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