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中国青少年的尿钙排泄情况。

Urinary calcium excretion in Chinese adolescents.

作者信息

Wong G W, Lam C W, Kwok M Y, Mak T W

机构信息

Department of Paediatrics, Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Territories.

出版信息

J Paediatr Child Health. 1998 Jun;34(3):226-8. doi: 10.1046/j.1440-1754.1998.00209.x.

Abstract

OBJECTIVES

To obtain normative reference values for urinary calcium excretion in Chinese adolescents.

METHODOLOGY

A random group of 425 healthy Chinese adolescents aged 12-19 years were recruited from secondary schools in Hong Kong. Each subject provided a sample of morning urine for the assessment of calcium and creatinine excretion. A subgroup of 80 subjects provided a 24-h urine sample for assessment of daily calcium excretion.

RESULTS

The mean (+/-S.D.) and median urinary calcium/creatinine concentration ratios (UCa/Cr) expressed in mmolmmol creatinine were 0.18 (+/-0.16) and 0.12. Girls had a higher UCa/Cr than boys (P < 0.0001). The mean+/-S.D. 24-h urinary calcium excretion was 0.043+/-0.025 mmol kg day(-1) (1.71+/-1.01 mg kg day(-1)).

CONCLUSION

The UCa/Cr ratio and 24-h urinary calcium excretion are low when compared with published values for Caucasian children. The apparent rarity of nephrolithiasis and microscopic haematuria associated with hypercalciuria may be related to the low urinary calcium excretion in this population.

摘要

目的

获取中国青少年尿钙排泄的标准参考值。

方法

从香港中学随机招募425名12至19岁的健康中国青少年。每位受试者提供一份晨尿样本,用于评估钙和肌酐排泄。80名受试者的亚组提供24小时尿样,用于评估每日钙排泄。

结果

以mmol/mmol肌酐表示的尿钙/肌酐浓度比值(UCa/Cr)的均值(±标准差)和中位数分别为0.18(±0.16)和0.12。女孩的UCa/Cr高于男孩(P<0.0001)。24小时尿钙排泄的均值±标准差为0.043±0.025 mmol·kg-1·天-1(1.71±1.01 mg·kg-1·天-1)。

结论

与白种儿童已发表的值相比,UCa/Cr比值和24小时尿钙排泄量较低。与高钙尿症相关的肾结石和镜下血尿明显少见,可能与该人群尿钙排泄量低有关。

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