Herman F, Delforge M, Bastens B, Masy V, Lilet H, Brassine A
Service de Gastro-Entérologie, Cliniques Saint-Joseph.
Rev Med Liege. 1998 Apr;53(4):193-8.
Sphincter of Oddi dysfunction (SOD) is an obstructive syndrome of the papilla not resulting from a stone. It may cause recurrent biliary type pain to cholecystectomized patients. SOD is caused by sphincter dyskinesia or benign stenosis. Diagnosis is usually based on symptoms, serum biochemistry, endoscopic retrograde cholangiopancreatography and Sphincter of Oddi manometry. The latter is the best means of evaluating Sphincter of Oddi dynamics. However, because of the many inconveniences of Sphincter of Oddi manometry and of its high morbidity rate, it is seldom used. Non invasive techniques, such as cholescintigraphy, have been developed to replace Sphincter of Oddi manometry in diagnosing SOD. Patients can be cured by sphincterotomy. Certain drugs could also be effective but few controlled studies have been carried out of date.
Oddi括约肌功能障碍(SOD)是一种并非由结石引起的乳头阻塞综合征。它可能会给接受胆囊切除术的患者带来反复发作的胆绞痛。SOD由括约肌运动障碍或良性狭窄引起。诊断通常基于症状、血清生化、内镜逆行胰胆管造影和Oddi括约肌测压。后者是评估Oddi括约肌动力的最佳方法。然而,由于Oddi括约肌测压存在诸多不便且发病率高,很少使用。已经开发出诸如胆闪烁造影等非侵入性技术来替代Oddi括约肌测压用于诊断SOD。患者可通过括约肌切开术治愈。某些药物可能也有效,但目前很少有对照研究。