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[急诊手术中的急性腹痛。450例患者的临床流行病学研究]

[Acute abdominal pain in emergency surgery. Clinical epidemiologic study of 450 patients].

作者信息

Caterino S, Cavallini M, Meli C, Murante G, Schiffino L, Lotito S, Toncher F

机构信息

I Istituto di Clinica Chirurgica, Università degli Studi di Roma La Sapienza.

出版信息

Ann Ital Chir. 1997 Nov-Dec;68(6):807-17; discussion 817-8.

PMID:9646542
Abstract

A retrospective study on 450 patients admitted in emergency with acute abdominal pain in a general surgical unit of the Ist Institute of Surgery of the University of Rome "La Sapienza" was carried out during a 7 years period. The aim of the study was to identify the most frequent causes of acute abdominal pain correlated with age, sex, onset of pain and other conditions in order to improve diagnosis and reduce mobility for mortality. Appendicitis was the most frequent diagnosis (75 pts = 16.4%). Non-specific abdominal pain (NSAP), found in 71 pts (15.5%), cholelithiasis in 57 pts (12.5%), abdominal malignancy in 47 pts (10.3%) were other frequent conditions. The largest number of admissions occurred in the age groups 60-70 years (16.6%) and 20-30 years (14.2%). Surgical operations were performed in 206 patients (45.7%). The overall mortality was 4.2% (19/450 pts) and the rate increased significantly in patients aged > 60 years. Postoperative mortality was 5.8% (12/206 pts) while mortality rate in non-operated patients was 2.8%. The causes of perioperative death included perforated peptic ulcer, abdominal malignancies (15.4%) and urgent colonic resections (9.4%). The duration of inpatients stay increased significantly with the age of the patients, including those with nsap. The results of the study indicate a need to review the methods of diagnosis of appendicitis and to obtain a better clinical performance in patients with nsap.

摘要

在罗马第一大学“La Sapienza”外科第一研究所普通外科,对450例因急性腹痛急诊入院的患者进行了一项为期7年的回顾性研究。该研究的目的是确定与年龄、性别、疼痛发作及其他情况相关的急性腹痛最常见病因,以改善诊断并降低死亡率。阑尾炎是最常见的诊断(75例 = 16.4%)。其他常见情况包括71例(15.5%)的非特异性腹痛(NSAP)、57例(12.5%)的胆石症、47例(10.3%)的腹部恶性肿瘤。入院人数最多的年龄组为60 - 70岁(16.6%)和20 - 30岁(14.2%)。206例患者(45.7%)接受了外科手术。总体死亡率为4.2%(19/450例),60岁以上患者的死亡率显著升高。术后死亡率为5.8%(12/206例),而非手术患者的死亡率为2.8%。围手术期死亡原因包括消化性溃疡穿孔、腹部恶性肿瘤(15.4%)和急诊结肠切除术(9.4%)。住院时间随患者年龄显著增加,包括患有NSAP的患者。研究结果表明需要重新审视阑尾炎的诊断方法,并在患有NSAP的患者中获得更好的临床疗效。

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