Shannon H M, Gillespie I N, Moss J G
Department of Radiology, Royal Infirmary of Edinburgh, Scotland.
AJR Am J Roentgenol. 1998 Jul;171(1):217-22. doi: 10.2214/ajr.171.1.9648792.
The purpose of the study was to evaluate the use of renal artery stents in the solitary functioning kidney of patients who have impaired renal function as a result of atherosclerotic renovascular disease by assessing primary patency, renal function outcome, and complication rates during a mean follow-up period of 15 months.
The Palmaz stent was placed in the arteries of 21 patients with solitary functioning kidneys. All patients had impaired renal function (creatinine level >150 micromol/l), and four patients were undergoing renal dialysis. Indications for stenting were recoil after percutaneous transluminal angioplasty (n = 12), arterial dissection after angioplasty (n = 2), restenosis after angioplasty (n = 1), and as the primary intervention (n = 6). Follow-up angiography was performed in 16 patients (76%).
Initial technical success was achieved in all patients (residual stenosis, <5%). At follow-up (range, 6-25 months), renal function had returned to normal in five patients (24%), improved in four patients (19%), stabilized in six patients (29%), and deteriorated in six patients (29%). Dialysis has been discontinued in all four dialysis patients. Major complications occurred in four patients (19%), including one death within 30 days of stenting. No significant restenoses were seen on follow-up angiography.
Placement of renal artery stents in the solitary kidney led to benefits in 70% of patients treated, including improved renal function in nine patients (43%) and stabilization in six patients (29%). In this high-risk group of patients, we advocate renal artery stenting as a relatively safe procedure to salvage the solitary kidney.
本研究的目的是通过评估在平均15个月的随访期内的原发性通畅率、肾功能转归和并发症发生率,来评价肾动脉支架在因动脉粥样硬化性肾血管疾病导致肾功能受损的患者的孤立功能肾中的应用情况。
将Palmaz支架置入21例孤立功能肾患者的动脉中。所有患者均存在肾功能受损(肌酐水平>150微摩尔/升),4例患者正在接受肾透析。支架置入的指征为经皮腔内血管成形术后回缩(n = 12)、血管成形术后动脉夹层(n = 2)、血管成形术后再狭窄(n = 1)以及作为初始干预措施(n = 6)。16例患者(76%)接受了随访血管造影。
所有患者均取得了初始技术成功(残余狭窄<5%)。在随访时(范围为6 - 25个月),5例患者(24%)的肾功能恢复正常,4例患者(19%)有所改善,6例患者(29%)保持稳定,6例患者(29%)恶化。所有4例透析患者均已停止透析。4例患者(19%)发生了主要并发症,包括1例在支架置入后30天内死亡。随访血管造影未发现明显的再狭窄。
在孤立肾中置入肾动脉支架使70%接受治疗的患者获益,包括9例患者(43%)肾功能改善和6例患者(29%)病情稳定。在这类高危患者中,我们主张肾动脉支架置入术是一种相对安全的挽救孤立肾的方法。