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一个基于系统命名法的可通过互联网访问的小鼠发育解剖学数据库。

An internet-accessible database of mouse developmental anatomy based on a systematic nomenclature.

作者信息

Bard J L, Kaufman M H, Dubreuil C, Brune R M, Burger A, Baldock R A, Davidson D R

机构信息

Centre for Developmental Biology and Department of Anatomy, Medical School, Edinburgh University, UK.

出版信息

Mech Dev. 1998 Jun;74(1-2):111-20. doi: 10.1016/s0925-4773(98)00069-0.

Abstract

This paper reports an internet-accessible database of mouse developmental anatomy (DMDA) that currently holds a hierarchy of the names and synonyms of the tissues in the first 22 Theiler stages of development (E1-E13.5), together with other appropriate information. The purposes of the database are to provide, first, a nomenclature for analyzing normal and mutant mouse anatomy, and second a language for inputting, storing and querying gene-expression and other spatially organized data. DMDA currently contains some 6900 named and staged tissues (e.g. 360 and 1161 tissues in Theiler stage (TS) 14 (E9) and TS22 (E13.5) embryos). DMDA will be extended to include further lineage and other data when it becomes available. The database can be interactively accessed over the internet using either a Java or a non-Java WWW browser at http://genex.hgu.mrc.ac.uk/.

摘要

本文报告了一个可通过互联网访问的小鼠发育解剖学数据库(DMDA),该数据库目前保存了发育的前22个泰勒阶段(E1 - E13.5)组织的名称和同义词层次结构,以及其他相关信息。该数据库的目的,一是为分析正常和突变小鼠解剖结构提供一种命名法,二是为输入、存储和查询基因表达及其他空间组织数据提供一种语言。DMDA目前包含约6900个命名和分期的组织(例如,泰勒阶段(TS)14(E9)和TS22(E13.5)胚胎中的360个和1161个组织)。当有更多谱系和其他数据可用时,DMDA将进行扩展以纳入这些数据。可使用Java或非Java的万维网浏览器通过互联网在http://genex.hgu.mrc.ac.uk/上交互式访问该数据库。

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